Disease Modifying Drugs

Betaferon

feeds@yuku.com (jacki) — Sun, 22 Jun 2008 17:15:38 GMT

Hi all, just wanted to report that I have been on this for a month. The flu type side effects have settled down, and are easily managed now. I have also mastered the injections. I would say it has been a rough month, but has been worth persevering. I just hope it works and reduces the relapses.

Beta interferon and atorvastatin combination may increase disease activity in multiple sclerosis.

feeds@yuku.com (squiffy2) — Wed, 18 Jun 2008 09:21:00 GMT

A combination treatment with interferon beta 1a and atorvastatin in people with MS was investigated. Surprisinglyit was found that people who took both medications had more relapses and more activity on MRI......

OBJECTIVE: To explore whether high dose atorvastatin can be administered...

First Human Studies for Multiple Sclerosis Drug Candidate, BaroFeron(TM) Initiated

feeds@yuku.com (squiffy2) — Mon, 16 Jun 2008 21:23:43 GMT

BaroFold Inc. announced that it has initiated a two-stage Phase 1, repeat dosing, single-center, double-blinded study in up to sixty healthy volunteers to determine the safety, tolerability, pharmacokinetics and pharmacodynamics of escalating doses of BaroFeron^(TM) (IFN beta-1b).

In published preclinical studies BaroFeron demonstrated enhanced pharmacological properties, both pharmacokinetics and pharmacodynamics, when compared to disease modifying therapies (DMTs) were presented and announced by Biogen Idec as poster presentations at the Consortium of Multiple...

itchy.......

feeds@yuku.com (sarah arbon) — Mon, 05 May 2008 09:17:47 GMT

hi all, does anyone suffer with injection site reactions redness and itchy scratchy feelings. using rebif if that has any bearing.

Possible new oral drug delivery system for Multiple Sclerosis Drugs

feeds@yuku.com (squiffy2) — Thu, 01 May 2008 13:59:22 GMT

Diabetics and multiple sclerosis patients could take their medicine via a capsule or a tablet instead of enduring multiple injections, because of a new development by a UT professor.

Biomedical engineering professor Nikolaos Peppas and other researchers created a gel-like material that could coat a capsule that would deliver protein-based medicine, such as insulin.

Diabetics, who usually inject themselves with insulin two to three times per day, could swallow a gel-coated...

Glatiramer acetate after induction therapy with mitoxantrone in relapsing multiple sclerosis

feeds@yuku.com (squiffy2) — Wed, 30 Apr 2008 07:14:34 GMT

Forty relapsing multiple sclerosis patients with 1-15 gadolinium (Gd)-enhancing lesions on screening brain magnetic resonance imaging (MRI) and Expanded Disability Status Scale (EDSS) scores 0-6.5 were randomized to receive short-term induction therapy with mitoxantrone (three monthly 12 mg/m(2) infusions) followed by 12...

Treatment of Multiple Sclerosis with AVONEX® (interferon Beta-1a) Enhances Quality of Life New Data Shows

feeds@yuku.com (squiffy2) — Thu, 17 Apr 2008 10:06:07 GMT

Results were released from a one-year prospective, observational study conducted to determine the impact of beginning treatment with AVONEX on MS patients' overall quality of life (QoL). The data showed that patients receiving treatment with AVONEX experienced statistically significant improvements in QoL, as measured by the EuroQol questionnaire (EQ-5D), compared to baseline.

In addition, the study demonstrated the negative impact of disability...

Early Treatment with COPAXONE® Significantly Delayed Progression to Clinically Definite Multiple Sclerosis

feeds@yuku.com (squiffy2) — Thu, 17 Apr 2008 07:44:12 GMT

Teva Seeks Approval for the Extension of its Indication to Include the Treatment of Patients with a First Clinical Event Suggestive of MS.

Teva Pharmaceutical Industries Ltd. announced new results from the PreCISe study, which demonstrated that early treatment with COPAXONE^® (glatiramer acetate injection) significantly reduced the risk of developing clinically definite multiple sclerosis (CDMS) by 45 percent compared to placebo...

copaxone and penicillin

feeds@yuku.com (vespula) — Mon, 07 Apr 2008 23:08:28 GMT

Can I ask if you take copaxone, and cant take Penicillin do you get nasty site's from injection's

Would love to hear your views

Thanks

Another New to site & Tysabri

feeds@yuku.com (sheena2007) — Sun, 06 Apr 2008 06:07:31 GMT

I got my Dx in mid 2-08 and was told ty was my best if not only hope. It seems I have had MS for a long time; I think since 1995.My 1st infusion was 3-18 with my next on 4-15. Here is the problem - have you ever heard of a sickly type person? Well that is me. I get sick if you look at me the wrong way. When I went in for the infusion I had a tiny cough, but I needed the infusion and had it. All was fine - great - till 2 days later. Just my luck, I came down with pneumonia. I went straight on...

ldn drug for ms

feeds@yuku.com (darcietwo) — Wed, 05 Mar 2008 21:15:11 GMT

Anyone else out there who has tries low dose naltrexone ? I've been on it for a few weeks with a couple of good results.

Lorna

tysabri infections

feeds@yuku.com (Unregistered(d)) — Fri, 15 Feb 2008 17:59:40 GMT

My husband 44 year old male ms since 2000 had 1 treatment of tysabri and experience skin breakdown double earinfection urinary tract infection and 2 types of sepsis. Think twice and get alot of information. I know its HOPE in a bag but my husband is really suffering after his week stay in the hospital. I just wanted to share

Martha's Tysabri Update February 2008

feeds@yuku.com (squiffy2) — Thu, 14 Feb 2008 12:37:11 GMT

Martha Rogers has just sent in a very encouraging update to her Tysabri Diary.

You can view this at MSRC: MSRC Interactive : Have Your Say : Tysabri User Diaries : Martha Rogers' Tysabri Diary

Squiffy's House Of Fun - Laughter For Multiple Sclerosis

New addition to the MSRC Tysabri Users Panel

feeds@yuku.com (squiffy2) — Wed, 13 Feb 2008 15:28:29 GMT

Hi all,

Paula has kindly joined the MSRC Tysabri Users Panel, and I placed her first tysabri Diary entry at MSRC: MSRC Interactive : Have Your Say : Tysabri User Diaries : Paula's Tysabri Diary

Thank you to Paula for volunteering to help other MSers by contributing her diary.

squiffs

Multiple Sclerosis Drug, Tysabri, May Be Linked to Melanoma

feeds@yuku.com (squiffy2) — Thu, 07 Feb 2008 12:13:38 GMT

Almost immediately after a 46-year-old woman with multiple sclerosis received her first dose of the drug Tysabri, a mole that had been on her shoulder for years suddenly took on a dangerous new character.

It turned out to be a melanoma that spread like wildfire. The woman now has just a few months to live.

At almost the same time, a 45-year-old woman who also has multiple sclerosis developed melanoma in her retina after receiving several doses of Tysabri. She had a family...

New information about multiple sclerosis and DMDs

feeds@yuku.com (squiffy2) — Thu, 31 Jan 2008 13:49:12 GMT

According to recent research from the United States, Results from an increasing number of clinical trials with disease-modifying drugs (DMDs) in multiple sclerosis (MS) become available, the challenge for the treating is how to decide on the appropriate therapy for an individual patient. An International Working Group for Treatment Optimization in MS met to consider how the principles of evidence-based medicine (EBM) should be used to assess the current best evidence regarding the treatment...

Rebif 1 Month On

feeds@yuku.com (Andyman 1968) — Sun, 13 Jan 2008 20:53:36 GMT

Hi all i have been taking Rebif for 1 month and think i may be slipping into another relapse. I am on the tritation pack and have built up from 8.8mg to 22mg and tomorrow (Mon 14th) i will be on a full 44mg dose. The flu like symptoms i have had from day one, a couple of ibuprofen and paracetimol tablets seem to do the trick and it only lasts a few hours the next...

baclofen

feeds@yuku.com (Unregistered(d)) — Thu, 10 Jan 2008 10:11:32 GMT

New to site & Tysabri

feeds@yuku.com (Unregistered(d)) — Tue, 08 Jan 2008 12:43:27 GMT

Hello, sorry if this is the wrong place to post but ive no clue. Ive recently stopped taking Rebif as i thought it was making my RRMS worse. And i have been looking into Tysabri on this site. Ive been hearing what i wanted to hear and at my next meeting with MS nurses i will be asking if i can be put on Tysabri. What im really wondering is are there any Tysabri diarys from people in the UK?

Thanks in advance
Wendy